Fluidized Bed Granulation: A Promising Technique
نویسندگان
چکیده
منابع مشابه
Granulation Time in Fluidized Bed Granulators
Size enlargement of fine powders by wet granulation involves mixing of fine particles with a binder liquid to form larger wet granules and drying them by evaporation of the binder liquid to form larger dry granules. Identification of the time for completion of granulation process is critical as further mixing of dry granules is providing extra energy for their attrition. In a batch fluidized be...
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Here, we statistically identified the critical factor of the granulation rate during the fluidized bed granulation process. Lactose was selected as the excipient and was granulated with several binders, including hydroxypropyl cellulose, hydroxypropyl methyl cellulose, and polyvinylpyrrolidone. The viscosity, density, and surface tension of the binder solution, contact angle, and the work done ...
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Ž . In this study, the rapid expansion of supercritical fluid solution RESS process was employed for the coating granulation of fine particles in a fluidized bed and its mechanism was examined. The rapid expansion of the supercritical solution causes very high supersaturating ratio of solute in the spraying flow, forming a large number of superfine nuclei. The superfine nuclei deposited on the ...
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In present paper, dynamic behavior and control of a fluidized bed reactor for polyethylene production has been considered. A double active sites model for Ziegler-Natta catalysts is used for simulation of polymerization reaction. Hydrodynamic behavior of the bed is modeled using a two phase model including bubble and emulsion phases in which bubble phase has plug flow pattern with different...
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ژورنال
عنوان ژورنال: International Journal of Pharmaceutical Sciences Review and Research
سال: 2020
ISSN: 0976-044X
DOI: 10.47583/ijpsrr.2020.v64i02.022